Successful Endoscopic Sclerotherapy Using Lauromacrogol Injection for Laryngopharyngeal Hemangioma.

Abstract

Objectives: This study aims to investigate the efficacy and safety of local lauromacrogol injection in the treatment of hypopharyngeal hemangioma. Methods: From Aug 2015 to May 2021, 13 consecutive patients suffering from hypopharyngeal hemangioma underwent local lauromacrogol injection assisted by endoscope in this prospective clinical series. All patients were followed up regularly and the therapeutic effects and complications were observed. Results: A total 13 of patients were enrolled, including 11 men and 2 women, with an average age of 48.5 years (range 25-76 years). The sizes of the hemangioma ranged from 0.5 × 1.0 cm to 3.5 × 3.5 cm. After 1 to 40 months of follow-up, 12 patients were cured and 1 was significantly effective after 1 to 4 (mean 1.8) injections. All patients suffered varying degrees of postoperative pain or foreign body sensation. 3 patients were significantly affected by local swelling of the injection site, 2 of which underwent prophylactic tracheostomy postoperatively and 1 patient returned to the ward with endotracheal intubation postoperatively. No complications such as mucosal ulceration, fever, and allergies occurred. Conclusions: Lauromacrogol injection is a safe and effective method to treat hypopharyngeal hemangioma.

• Authors: Hongyang Qu, Xia Lei, Lin Hu, Xiao Yin, Xiaodong Du, Lei Zhang, Changling Sun
• Journal: Ear, nose, & throat journal (Ear Nose Throat J) Vol. 100 Issue 9 Pg. 662-666 (Nov 2021) ISSN: 1942-7522 [Electronic] United States
• PMID: 34551625 (Publication Type: Journal Article)

Chemical References

• Sclerosing Solutions
• Polidocanol

Topics

• Adult
• Aged
• Endoscopy
• Female
• Hemangioma (therapy)
• Humans
• Hypopharyngeal Neoplasms (therapy)
• Injections
• Male
• Middle Aged
• Polidocanol (administration & dosage)
• Sclerosing Solutions (administration & dosage)
• Sclerotherapy (methods)