Pain modulation induced by electronic wrist-ankle acupuncture: A functional near-infrared spectroscopy study.

Abstract

BACKGROUND:

As a new technology, electronic wrist-ankle acupuncture (E-WAA) combines the advantages of wrist-ankle acupuncture and transcutaneous electrical nerve stimulation, but the analgesic effect and mechanism need to be clarified. The purpose of this study was to identify the pain modulation caused by E-WAA by evaluating the response of the prefrontal cortex (PFC) from the perspective of neurophysiology.

METHODS:

Fifty male volunteers (age 25.00 ± 1.05 years) with trapezius myofascial pain syndrome were randomly allocated into intervention group (E-WAA treatment) or sham control group at a 1:1 ratio. An outcome evaluation system was used to induce tenderness on the Jianjing point and record the pain value. A multichannel functional near-infrared spectroscope was used to detect the PFC activation during tenderness before and after treatment to demonstrate the neuromodulation mechanism. A general linear model and t-test (p < 0.05) were used to analyze the difference in the oxyhemoglobin (HbO) concentration and pain value.

RESULTS:

In the intervention group, the pain value of volunteers decreased significantly (p = 0.017) after E-WAA treatment, whereas there was no statistical difference (p = 0.082) in the sham group. Before treatment, the frontopolar (FP) and dorsolateral prefrontal cortex (DLPFC) were the activation areas of the PFC. The E-WAA treatment then suppressed the activation of the two areas. The HbO concentration of the FP and DLPFC changed from a sharp rise during tenderness to not changing with tenderness stimulation.

CONCLUSION:

The results demonstrated that the E-WAA have a great analgesic effect. The FP and DLPFC were relative to the analgesia neuromodulation induced by the E-WAA.

• Authors: Ping Shi, Junwen Liu, Jiahao Du, Hongliu Yu, Fanfu Fang
• Journal: Pain practice : the official journal of World Institute of Pain (Pain Pract) Vol. 22 Issue 2 Pg. 182-190 (02 2022) ISSN: 1533-2500 [Electronic] United States
• PMID: 34519161 (Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
• Copyright: © 2021 World Institute of Pain.

Topics

• Acupuncture Therapy (methods)
• Adult
• Ankle
• Electronics
• Humans
• Male
• Pain
• Spectroscopy, Near-Infrared
• Wrist
• Young Adult