Abstract | BACKGROUND: CASE PRESENTATION: We herein reported a patient with a two-year history of painless and reduced visual acuity in both eyes who received tamoxifen therapy for 6 years. Tamoxifen-induced rentinopathy with CME showed significant development even though the patient has already discontinued tamoxifen treatment for 6 months. Anatomic improvements after intravitreal ranibizumab injection in both eyes were significant but were temporary. Surprisingly, CME in both eyes has been resolved spontaneously after 10 months in the penultimate visit without any therapy. CONCLUSION: Intravitreal ranibizumab injection temporarily improved the anatomy of the eyes in a case with tamoxifen-induced CME, and only tamoxifen withdrawal can bring a sustained effect.
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Authors | Chuanyu Li, Jun Xiao, He Zou, Bo Yang, Lifu Luo |
Journal | BMC ophthalmology
(BMC Ophthalmol)
Vol. 21
Issue 1
Pg. 201
(May 07 2021)
ISSN: 1471-2415 [Electronic] England |
PMID | 33962570
(Publication Type: Journal Article)
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Chemical References |
- Tamoxifen
- Bevacizumab
- Ranibizumab
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Topics |
- Bevacizumab
(therapeutic use)
- Humans
- Intravitreal Injections
- Macular Edema
(chemically induced, drug therapy)
- Ranibizumab
(therapeutic use)
- Tamoxifen
(adverse effects)
- Tomography, Optical Coherence
- Visual Acuity
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