Abstract | OBJECTIVES: METHODS: Phlebotomus argentipes sandflies were collected from the visceral-leishmaniasis endemic states of Bihar, Jharkhand and West Bengal. In the WHO tube tests, the phenotypic susceptibility of F1, 2-day old, non-blood fed females were determined against filter papers impregnated with DDT 4%, malathion 5%, pirimiphos-methyl 0.25%, alpha-cypermethrin 0.05%, deltamethrin 0.05%, lambda-cyhalothrin 0.05%, permethrin 0.75%, bendiocarb 0.1% and propoxur 0.1%, which were sourced from Universiti Sains Malaysia. The knockdown of sandflies after 1-h exposure and mortality at 24 h after the 1-h exposure period were scored. RESULTS: Mean mortality of P. argentipes 24 h after exposure in tube tests was 22.6% for DDT and ≥ 98% for other insecticide-impregnated papers tested. CONCLUSION: Phlebotomus argentipes continues to be highly resistant to DDT with no reversal of resistance after DDT's withdrawal from IRS. P. argentipes was fully susceptible to pyrethroid, organophosphate and carbamate insecticides tested. Regular monitoring is warranted for insecticide resistance management in sandfly vectors.
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Authors | Diwakar S Dinesh, Faizan Hassan, Vijay Kumar, Shreekant Kesari, Roshan K Topno, Rajpal S Yadav |
Journal | Tropical medicine & international health : TM & IH
(Trop Med Int Health)
Vol. 26
Issue 7
Pg. 823-828
(07 2021)
ISSN: 1365-3156 [Electronic] England |
PMID | 33733549
(Publication Type: Journal Article)
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Copyright | © 2021 John Wiley & Sons Ltd. |
Chemical References |
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Topics |
- Animals
- Humans
- India
- Insect Vectors
(drug effects)
- Insecticide Resistance
(drug effects)
- Insecticides
(pharmacology)
- Leishmaniasis, Visceral
(prevention & control)
- Phlebotomus
(drug effects)
- Psychodidae
(drug effects)
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