The Comparison of Sarcopenia Diagnostic Criteria using AWGS 2019 with the Other Five Criteria in West China.

Abstract

INTRODUCTION:

The aim of this study was to investigate the prevalence and associated factors of sarcopenia defined by different criteria in community-dwelling adults of west China using the baseline data of West-China Health and Aging Trend (WCHAT) study.

METHODS:

Adults aged 50 years or older in communities of Yunnan, Guizhou, Sichuan, and Xinjiang provinces were enrolled in this study. We applied 6 -diagnostic criteria (AWGS 2019, AWGS 2014, EWGSOP1, -EWGSOP2, IWGS, and FNIH) to define sarcopenia. Muscle mass was measured based on bioimpedance analysis. Handgrip strength and walking speed were recorded, respectively. Different variables like anthropometry measures, lifestyles, chronic disease, and blood test were collected.

RESULTS:

We included 4,500 participants. The prevalence of sarcopenia was 22.8, 19.3, 57.1, 11.8, 24.1, and 18.1% according to the AWGS 2019, AWGS 2014, EWGSOP 1, EWGSOP 2, IWGS, and FNIH criteria, respectively. We found that serum albumin level was independently associated with sarcopenia using AWGS 2019 and IWGS. And vitamin D level was independently associated with sarcopenia using AWGS 2014, -EWGSOP2, and FNIH. While age, depressive status, BMI, hemoglobin, vitamin D, and insulin level were all significantly associated with sarcopenia using AWGS 2014, but all of these factors were not significant using AWGS 2019.

CONCLUSIONS:

Sarcopenia was highly prevalent in west China regardless of the diagnostic criteria. Serum albumin and vitamin D level were mostly associated with sarcopenia defined by different criteria. While most risk factors associated with the AWGS 2014-defined sarcopenia exhibited no consistent pattern with AWGS 2019, the validity of the AWGS 2019 consensus needs to be confirmed in further prospective studies.

• Authors: Xiaolei Liu, Lisha Hou, Wanyu Zhao, Xin Xia, Fengjuan Hu, Gongchang Zhang, Qiukui Hao, Lixing Zhou, Yixin Liu, Meiling Ge, Yan Zhang, Jirong Yue, Birong Dong
• Journal: Gerontology (Gerontology) Vol. 67 Issue 4 Pg. 386-396 ( 2021) ISSN: 1423-0003 [Electronic] Switzerland
• PMID: 33596568 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: © 2021 S. Karger AG, Basel.

Topics

• China (epidemiology)
• Hand Strength
• Humans
• Prevalence
• Prospective Studies
• Sarcopenia (diagnosis, epidemiology)
• Walking Speed