[SARS-CoV-2 and neurological disorders: the revelance of biomarkers?]

Abstract

Soon after the pandemic, numerous publications described cases of neurological disorders associated with the SARS-CoV-2 infection. The range of neurological symptoms is becoming increasingly more extensive as the pandemic progresses. However, it is not yet well established whether the manifestations are due to direct viral damage to the nervous system or indirect consequences of the infection. This review presents an inventory of the biochemical markers studied in the context of neurological disorders related to SARS-CoV-2. By reflecting various physiopathological mechanisms, these biomarkers allow both a better understanding of the pathophysiology of Covid-19 and a contribution to the diagnosis of neurologic troubles; they could participate in the prognostic evaluation of patients.

• Authors: Edith Bigot-Corbel, Aymeric Lanore, Celia Raulet, Cécile Delorme, Jean-Philippe Azulay, Sylvain Lehmann, Jean-Louis Beaudeux, Marie-Christine Beauvieux, Vincent Sapin, Katell Peoc'h, Benoit Rucheton, Membres du groupe de travail « SFBC Marqueurs biochimiques COVID-19 »
• Journal: Annales de biologie clinique (Ann Biol Clin (Paris)) Vol. 79 Issue 1 Pg. 7-16 (02 01 2021) ISSN: 1950-6112 [Electronic] France
• Vernacular Title: SARS-CoV-2 et atteintes neurologiques : quelle est la place des biomarqueurs ?
• PMID: 33570039 (Publication Type: Journal Article, Review)

Chemical References

• Biomarkers

Topics

• Biomarkers (analysis)
• COVID-19 (complications, diagnosis, epidemiology)
• Disease Progression
• Humans
• Nervous System Diseases (diagnosis, epidemiology, etiology, virology)
• Pandemics
• Predictive Value of Tests
• Prognosis
• SARS-CoV-2 (physiology)