Influence of Sex on Outcomes After Thoracic Endovascular Repair for Type B Aortic Dissection.

Abstract

We aimed to investigate whether sex differences influence the clinical outcomes of patients who undergo thoracic endovascular aortic repair (TEVAR) for type B aortic dissection (TBAD). We retrospectively analyzed a prospectively maintained single-center cohort of patients with TBAD who underwent TEVAR between January 2010 and June 2017. We evaluated the in-hospital and long-term mortality and composite end point. Of the 913 patients, 793 (86.8%) were male and 120 (13.1%) were female. Compared to male patients, the female patients were older, more likely to have diabetes mellitus, but less likely to smoke or have hypertension. The proximal landing zone in 0 and 1 was higher in male patients (P = .023), who were more likely to require an aortic arch bypass. Endoleak, delirium, and ICU stay after stent-graft implantation were also more frequent in men. Sex factor was not associated with in-hospital or long-term mortality or the composite end point in the multivariable regression analyses and Cox regression model. The mean estimated survival time was similar between males and females (2462.9 ± 141.2 vs 2804.1 ± 117.4 days, P = .167) in the propensity score-matched cohort. Despite distinct characteristics between sex, there was no sex-related difference in long-term clinical outcomes after TEVAR for TBAD.

• Authors: Songyuan Luo, Yi Zhu, Enmin Xie, Huanyu Ding, Fan Yang, Lyufan Chen, Jitao Liu, Yuan Liu, Ling Xue, Ruixin Fan, JianFang Luo, Jiyan Chen
• Journal: Angiology (Angiology) Vol. 72 Issue 6 Pg. 556-564 (Jul 2021) ISSN: 1940-1574 [Electronic] United States
• PMID: 33504166 (Publication Type: Comparative Study, Journal Article, Observational Study)

Topics

• Adult
• Age Factors
• Aged
• Aortic Dissection (diagnostic imaging, mortality, surgery)
• Aortic Aneurysm, Thoracic (diagnostic imaging, mortality, surgery)
• Blood Vessel Prosthesis Implantation (adverse effects, mortality)
• Comorbidity
• Endovascular Procedures (adverse effects, mortality)
• Female
• Health Status Disparities
• Hospital Mortality
• Humans
• Male
• Middle Aged
• Postoperative Complications (mortality)
• Retrospective Studies
• Risk Assessment
• Risk Factors
• Sex Factors
• Time Factors
• Treatment Outcome