[Research progress on circular RNA in oral squamous cell carcinoma].

Abstract

Circular RNA, a non-coding RNA that forms a covalently closed continuous loop, exists widely in eukaryotic cells. The biogenesis and biological function of this type of RNA indicate that it can play a crucial role in diseases such as tumors, neural system diseases, and cardiovascular diseases; moreover, this RNA may have great potential use as a biomarker in these diseases. Oral squamous cell carcinoma (OSCC) is a common malignancy in oral surgery that is difficult to cure, metastasizes easily, and has poor prognosis. In this review, we summarize the loop-forming mechanisms and functions of circular RNA and describe the progress of current research in the development of oral cancer.

• Authors: Ke-Xin Lei, He-Tian Bai, Song-Yue Yang, Jing Li, Qian-Ming Chen
• Journal: Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology (Hua Xi Kou Qiang Yi Xue Za Zhi) Vol. 38 Issue 4 Pg. 425-430 (Aug 01 2020) ISSN: 2618-0456 [Electronic] China
• PMID: 32865363 (Publication Type: Journal Article, Review)

Chemical References

• RNA, Circular
• RNA

Topics

• Carcinoma, Squamous Cell
• Humans
• Mouth Neoplasms
• RNA
• RNA, Circular