Abstract | BACKGROUND: METHODS: We assessed 13 patients with T2DM undergoing hemodialysis. They simultaneously underwent FGM, continuous glucose monitoring (CGM, iPro2), and self-monitoring blood glucose (SMBG). RESULTS: Parkes error grid analysis against SMBG showed that 49.0% and 51.0% of interstitial fluid glucose (ISFG) levels measured using FGM and 93.3% and 6.7% of those measured using CGM fell into zones A and B, respectively. Mean absolute relative difference (MARD) against SMBG for FGM was significantly higher than that for CGM (19.5% ± 13.2% vs 8.1% ± 7.6%, P < .0001). Parkes error grid analysis of 2496 paired ISFG levels between FGM and CGM showed that 53.6%, 46.2%, and 0.2% of the plots fell into zones A, B, and C, respectively. Mean ISFG levels were lower with FGM than with CGM (143.7 ± 67.2 mg/dL vs 164.6 ± 58.5 mg/dL; P < .0001). Mean absolute relative difference of ISFG levels between FGM and CGM was 19.2% ± 13.8%. Among three groups classified according to CGM ISFG levels ( hypoglycemia, <70 mg/dL; euglycemia, 70-180 mg/dL; and hyperglycemia, >180 mg/dL), the MARDs for hypoglycemia (31.9% ± 25.0%) and euglycemia (22.8% ± 14.6%) were significantly higher than MARD for hyperglycemia (13.0% ± 8.5%) (P < .0001 in both). CONCLUSIONS: Flash glucose monitoring may be clinically acceptable. Average ISFG levels were lower with FGM than with CGM, and MARDs were higher for hypoglycemia and euglycemia in patients with T2DM undergoing hemodialysis.
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Authors | Takahiro Yajima, Hiroshi Takahashi, Keigo Yasuda |
Journal | Journal of diabetes science and technology
(J Diabetes Sci Technol)
Vol. 14
Issue 6
Pg. 1088-1094
(11 2020)
ISSN: 1932-2968 [Electronic] United States |
PMID | 31625413
(Publication Type: Comparative Study, Journal Article)
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Chemical References |
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Topics |
- Aged
- Biomarkers
(metabolism)
- Blood Glucose
(metabolism)
- Blood Glucose Self-Monitoring
(instrumentation)
- Diabetes Mellitus, Type 2
(blood, diagnosis, diet therapy)
- Equipment Design
- Extracellular Fluid
(metabolism)
- Female
- Humans
- Kidney Diseases
(blood, diagnosis, therapy)
- Male
- Middle Aged
- Monitoring, Ambulatory
(instrumentation)
- Predictive Value of Tests
- Renal Dialysis
(adverse effects)
- Reproducibility of Results
- Time Factors
- Treatment Outcome
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