Abstract | BACKGROUND: OBJECTIVES AND METHODS: RESULTS: CONCLUSIONS: Platelet polyphosphate and Zn2+ can promote subsets of the reactions of the contact pathway, with implications for a variety of disease states.
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Authors | Yuqi Wang, Ivan Ivanov, Stephanie A Smith, David Gailani, James H Morrissey |
Journal | Journal of thrombosis and haemostasis : JTH
(J Thromb Haemost)
Vol. 17
Issue 12
Pg. 2131-2140
(12 2019)
ISSN: 1538-7836 [Electronic] England |
PMID | 31420909
(Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't)
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Copyright | © 2019 International Society on Thrombosis and Haemostasis. |
Chemical References |
- Kininogen, High-Molecular-Weight
- Polyphosphates
- Factor Xa
- Zinc
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Topics |
- Blood Coagulation
- Enzyme Activation
- Factor Xa
(metabolism)
- Humans
- Kinetics
- Kininogen, High-Molecular-Weight
(blood, chemistry)
- Molecular Weight
- Polyphosphates
(blood, chemistry)
- Proteolysis
- Zinc
(blood)
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