Abstract | BACKGROUND: METHODS: For the prevalence study, 327 sera collected in 2013 and 2014 were tested for anti-SFV and anti-WNV IgG using indirect immunofluorescence assay and ELISA, respectively. In order to investigate a possible role of SFV and WNV in CNS infections, 127 sera of patients presenting symptoms of SFV or WNV infections were screened for IgM specific to SFV and WNV. RESULTS: The overall anti-SFV IgG seroprevalence was 28% and was increasing with age (P< 0.01). The seroprevalence rate for anti-WNV IgG in Cyprus was 5%. Concerning the role of SFVs in CNS infections, anti-SFV IgM was detected in 8 out of 127 sera from selected patients presenting relevant symptoms of infections during vector's active period. In addition, anti-WNV IgM were detected in 17 out of the 127 patients with compatible symptoms. CONCLUSION: The findings confirm the presence of sandfly fever and WNV in Cyprus and should, therefore, be considered in the differential diagnosis of patients with febrile illness/ meningitis.
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Authors | Gaetan Billioud, Christina Tryfonos, Jan Richter |
Journal | Journal of arthropod-borne diseases
(J Arthropod Borne Dis)
Vol. 13
Issue 1
Pg. 116-125
(Mar 2019)
ISSN: 2322-1984 [Print] Iran |
PMID | 31346541
(Publication Type: Journal Article)
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