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Accentuation of J waves by intracoronary administration of multiple agents in a patient with vasospastic angina: Implications for pathogenesis.

Abstract
A 64-year-old man was resuscitated from out-of-hospital VF, and coronary spasm was provoked by ergonovine at catheterization. An ECG was analyzed before and after each intracoronary injection of drugs or contrast medium. The baseline ECG showed nondiagnostic J waves in leads II, III, and aVF, but administration of acetylcholine, contrast medium and nitroglycerin into the right coronary artery induced a distinct augmentation of J-wave amplitudes with changes in the QRS morphology. Transient ischemia induced by the intracoronary administration of these agents seemed to be the mechanism underlying the increase in J-wave amplitudes.
AuthorsYuta Sakaguchi, Koichi Fuse, Hitoshi Kitazawa, Yoshio Ikeda, Takao Sato, Masaaki Okabe, Yoshifusa Aizawa
JournalJournal of electrocardiology (J Electrocardiol) 2019 Sep - Oct Vol. 56 Pg. 34-37 ISSN: 1532-8430 [Electronic] United States
PMID31252339 (Publication Type: Case Reports, Journal Article)
CopyrightCopyright © 2019. Published by Elsevier Inc.
Chemical References
  • Acetylcholine
  • Ergonovine
Topics
  • Acetylcholine
  • Angina Pectoris, Variant
  • Coronary Angiography
  • Coronary Vasospasm (chemically induced, complications, diagnosis)
  • Coronary Vessels
  • Electrocardiography
  • Ergonovine
  • Humans
  • Male
  • Middle Aged

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