HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Ultrasound-guided preoperative single-dose erector spinae plane block provides comparable analgesia to thoracic paravertebral block following thoracotomy: a single center randomized controlled double-blind study.

AbstractBACKGROUND:
Thoracic paravertebral block (TPVB) technique for thoracotomy has seen increased application. The erector spinae plane block (ESPB) technique is simpler to perform than TPVB. However, whether it can be employed as a safe alternative analgesic technique has not been verified by a head-to-head clinical study.
METHODS:
Ninety-four patients scheduled for thoracotomy lung surgeries were randomly allocated to an ESPB or TPVB group. Patients in both groups were provided with an intravenous patient-controlled analgesia (PCA) device containing sufentanil. Visual analogue scale (VAS) pain scores under the status of rest and cough were recorded at 1, 6, 12, and 24 h postoperatively. In addition, total press times of PCA were read from the PCA memory. The adverse effects, puncture time and success rate of one puncture were also recorded.
RESULTS:
There were no significant differences in pain scores at rest and cough between the ESPB and TPVB groups in each of the first two days after surgery, and no difference between the two groups was identified regarding postoperative sufentanil usage (P>0.05). There was no statistical difference in post-operative nausea and vomiting. There was significantly less hypotension (6.7% vs. 21.7%, P=0.04), bradycardia (0 vs. 8.7%, P=0.04), hematoma (0 vs. 10.9%, P=0.02) and a higher success rate of one puncture (82.2% vs. 54.3%, P<0.001) in the ESPB group.
CONCLUSIONS:
Preoperative single-injection ESPB plus postoperative sufentanil PCA provided similar effects of pain relief for patients undergoing thoracotomy when comparing to TPVB. Yet, ESPB had the advantages of a lower adverse effect incidence.
AuthorsBin Fang, Zhaomin Wang, Xiaojing Huang
JournalAnnals of translational medicine (Ann Transl Med) Vol. 7 Issue 8 Pg. 174 (Apr 2019) ISSN: 2305-5839 [Print] China
PMID31168455 (Publication Type: Journal Article)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: