Abstract |
Little is known about how Treg cells mediate suppression, especially in tissues. In this issue of Immunity, Schmidleithner et al. report that Treg cells catabolize PGE2 into 15-keto-PGE2, a T cell-inhibitory metabolite, and that this mechanism controls inflammation in adipose tissue.
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Authors | Dan Wu, Megan K Levings |
Journal | Immunity
(Immunity)
Vol. 50
Issue 5
Pg. 1122-1124
(05 21 2019)
ISSN: 1097-4180 [Electronic] United States |
PMID | 31117006
(Publication Type: Journal Article, Comment)
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Copyright | Copyright © 2019 Elsevier Inc. All rights reserved. |
Topics |
- Adipose Tissue
- Animals
- Homeostasis
- Humans
- Inflammation
- Mice
- T-Lymphocytes, Regulatory
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