Use of enzymes in typing group A beta-haemolytic streptococci.

Abstract

A series of 698 strains of group A beta-haemolytic streptococci (GAS) isolated from children with streptococcal pyoderma was tested for production of serum opacity factor (OF) and nicotinamide adenine dinucleotide glycohydrolase (NADase). OF was produced by 37% of strains and 40% produced NADase. Classification based on various combinations of OF and NADase reactions showed that 58% belonged to enzyme group el and 34% to e2. Correlation with T and M types showed the possible use of this means of classification as an epidemiological marker for GAS. The specificity of such a system in the further classification of various T types of GAS in epidemiological studies, in the light of antigenic variation among M types, is described.

• Authors: K N Brahmadathan, G Koshi
• Journal: Journal of medical microbiology (J Med Microbiol) Vol. 27 Issue 2 Pg. 141-4 (Oct 1988) ISSN: 0022-2615 [Print] England
• PMID: 3050113 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Topics

• Bacterial Typing Techniques (methods)
• Child
• Humans
• Pyoderma (microbiology)
• Streptococcus pyogenes (classification, enzymology)