Dual-Phase 18F-FP-CIT PET in Corticobasal Syndrome.

Abstract

Corticobasal syndrome is the most common phenotype of corticobasal degeneration (CBD). F-FP-CIT PET and MRI are not helpful in distinguishing CBD from idiopathic Parkinson disease. Dual-phase F-FP-CIT PET is a recently developed imaging that shows regional cerebral perfusion in the early phase and dopamine transporter density in the late phase. We investigated the usefulness of dual-phase F-FP-CIT PET imaging in 3 patients with corticobasal syndrome. This image highlights that the early phases of F-FP-CIT PET may reflect regional cerebral perfusion with a pattern very similar to that of regional glucose metabolism in CBD.

• Authors: Je Hong Min, Dong Gyu Park, Jung Han Yoon, Young Sil An
• Journal: Clinical nuclear medicine (Clin Nucl Med) Vol. 44 Issue 1 Pg. e49-e50 (Jan 2019) ISSN: 1536-0229 [Electronic] United States
• PMID: 30371594 (Publication Type: Case Reports, Journal Article)

Chemical References

• Radiopharmaceuticals
• Tropanes
• 2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane

Topics

• Brain (diagnostic imaging)
• Diagnosis, Differential
• Humans
• Neurodegenerative Diseases (diagnostic imaging)
• Positron Emission Tomography Computed Tomography
• Radiopharmaceuticals
• Tropanes