Whole blood exchange transfusion as a promising treatment of aluminium phosphide poisoning.

Abstract

A 37-year-old male was referred to us about one hour after deliberate ingestion of two 3-gram aluminium phosphide (ALP) tablets. Three hours after admission, his blood pressure dropped to 85/55 mmHg, his heart rate increased to 120 bpm, O2 saturation dropped to 82 %, and the electrocardiogram showed junctional rhythm. We started whole blood exchange, and gross haematuria and jaundice ensued. However, his blood pressure increased, arrhythmia resolved itself, and he was extubated two days after the transfusion was completed. He was sent home seven days after admission completely symptom-free. We believe this treatment may be successfully applied in ALP-poisoned patients.

• Authors: Nasim Zamani, Hossein Hassanian-Moghaddam, Sakine Ebrahimi
• Journal: Arhiv za higijenu rada i toksikologiju (Arh Hig Rada Toksikol) Vol. 69 Issue 3 Pg. 275-277 (Sep 01 2018) ISSN: 1848-6312 [Electronic] Croatia
• PMID: 30285939 (Publication Type: Case Reports, Journal Article)

Chemical References

• Aluminum Compounds
• Pesticides
• Phosphines
• aluminum phosphide

Topics

• Adult
• Aluminum Compounds (poisoning)
• Blood Transfusion (methods)
• Humans
• Iran
• Male
• Pesticides (poisoning)
• Phosphines (poisoning)
• Poisoning (therapy)
• Treatment Outcome