Abstract | BACKGROUND: METHODS: A total of 853 patients who underwent primary TJA were finally included in this retrospective study. Acute DVT after TJA was evaluated by venography. Preoperative and postoperative LMR and MHR were calculated according to the blood routine test and blood biochemistry test. The association between LMR or MHR and DVT and their predictive value were evaluated by multiple logistic regression analysis and ROC curve respectively. RESULTS: Totally, 126 patients (14.8%) were diagnosed with DVT by venography. Patients with DVT had a significantly higher level of preoperative MHR (P < 0.001) and postoperative MHR (P < 0.001), along with a significantly lower level of preoperative LMR (P < 0.001) and postoperative LMR (P < 0.001). Multiple logistic regression indicated that BMI (OR = 1.10, P = 0.001), preoperative LMR (OR = 0.72, P<0.001), and postoperative LMR (OR = 0.32, P < 0.001) were independent risk factors for DVT. Besides, BMI (OR = 1.17, P = 0.001), female (OR = 4.6, P = 0.004), preoperative MHR (OR = 10.43, P = 0.008), postoperative Hb (OR = 0.96, P = 0.002), and postoperative LMR were independently associated with symptomatic DVT. The ROC curve suggested that the postoperative LMR had a potential to predict DVT after TJA. CONCLUSION: In summary, the present study found out a significant association of perioperative LMR or MHR with DVT after TJA. Moreover, the postoperative LMR had a potential to predict DVT accurately.
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Authors | Xiaobo Zhu, Yao Yao, Chen Yao, Qing Jiang |
Journal | Journal of orthopaedic surgery and research
(J Orthop Surg Res)
Vol. 13
Issue 1
Pg. 211
(Aug 24 2018)
ISSN: 1749-799X [Electronic] England |
PMID | 30143011
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Aged
- Arthroplasty, Replacement
(adverse effects)
- Female
- Humans
- Lipoproteins, HDL
(blood)
- Lymphocytes
- Male
- Middle Aged
- Monocytes
- Retrospective Studies
- Venous Thrombosis
(diagnosis, etiology)
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