Abstract |
Tobacco mosaic virus coat protein was modified with a small molecular fluorous ponytail at specific sites, and self-assembled into spherical nanoparticles through fluorous interaction induced self-assembly. By loading the anti- cancer drug cisplatin through metal- ligand coordination, this spherical assembly with high stability has potential as a drug carrier.
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Authors | Sijia Gao , Xiangxiang Liu , Zhaocheng Wang , Shidong Jiang , Man Wu , Ye Tian , Zhongwei Niu |
Journal | Nanoscale
(Nanoscale)
Vol. 10
Issue 25
Pg. 11732-11736
(Jul 05 2018)
ISSN: 2040-3372 [Electronic] England |
PMID | 29911244
(Publication Type: Journal Article)
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Chemical References |
- Capsid Proteins
- Drug Carriers
- H protein, Tobacco mosaic virus
- Fluorine
- Cisplatin
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Topics |
- Capsid Proteins
(chemistry)
- Cisplatin
(administration & dosage)
- Drug Carriers
(chemistry)
- Fluorine
(chemistry)
- HeLa Cells
- Humans
- Nanoparticles
(chemistry)
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