Abstract |
One of the characteristics of picornavirus infection of cells in tissue culture is a specific inhibition of utilization of host cell mRNA for protein synthesis. In this study we show that human rhinovirus 14 is similar to poliovirus in that the inhibition of host cell translation that occurs during infection correlates with the proteolytic cleavage of an Mr 220,000 subunit of the cap-binding protein complex.
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Authors | D Etchison, S Fout |
Journal | Journal of virology
(J Virol)
Vol. 54
Issue 2
Pg. 634-8
(May 1985)
ISSN: 0022-538X [Print] United States |
PMID | 2985827
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
- Carrier Proteins
- Peptide Initiation Factors
- RNA Cap-Binding Proteins
- Globins
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Topics |
- Carrier Proteins
(metabolism)
- Globins
(biosynthesis)
- HeLa Cells
(microbiology)
- Humans
- Molecular Weight
- Peptide Initiation Factors
(isolation & purification)
- Protein Biosynthesis
- RNA Cap-Binding Proteins
- Rhinovirus
(genetics, metabolism)
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