Manual Compared With Electric Vacuum Aspiration for Treatment of Molar Pregnancy.
Abstract | OBJECTIVE: To evaluate uterine evacuation of patients with molar pregnancy, comparing manual with electric vacuum aspiration. METHODS: RESULTS: Among 1,727 patients with molar pregnancy, 1,206 underwent electric vacuum aspiration and 521 underwent manual vacuum aspiration. After human chorionic gonadotropin normalization, patients with benign molar pregnancy were followed for 6 months and patients treated for gestational trophoblastic neoplasia were followed for 12 months. Baseline risk factors for gestational trophoblastic neoplasia and demographic features were similar between the treatment groups. Uterine synechia developed less frequently after manual vacuum aspiration than after electric vacuum aspiration, 6 of 521 vs 63 of 1,206 (adjusted odds ratio [OR] 0.21, 95% CI 0.09-0.49), despite no differences in the occurrence of incomplete uterine evacuation, 65 of 521 vs 161 of 1,206 (adjusted OR 0.93, 95% CI 0.69-1.27), development of postmolar gestational trophoblastic neoplasia, 90 of 521 vs 171 of 1,206 (adjusted OR 1.26, 95% CI 0.96-1.67), or the need for multiagent chemotherapy, 22 of 521 vs 41 of 1,206 (adjusted OR 0.81, 95% CI 0.73-1.28). CONCLUSION: Manual vacuum aspiration appears to be similar to electric vacuum aspiration for treatment of molar pregnancy and may be associated with less development of uterine synechia.
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Authors | Lilian Padrón, Jorge Rezende Filho, Joffre Amim Junior, Sue Yazaki Sun, Rafael Cortés Charry, Izildinha Maestá, Kevin M Elias, Neil Horowitz, Antonio Braga, Ross S Berkowitz |
Journal | Obstetrics and gynecology
(Obstet Gynecol)
Vol. 131
Issue 4
Pg. 652-659
(04 2018)
ISSN: 1873-233X [Electronic] United States |
PMID | 29528932
(Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Adolescent
- Adult
- Brazil
- Child
- Chorionic Gonadotropin
(blood)
- Female
- Humans
- Hydatidiform Mole
(pathology, surgery)
- Logistic Models
- Middle Aged
- Multivariate Analysis
- Neoplasm Staging
- Pregnancy
- Retrospective Studies
- Risk Factors
- Vacuum Curettage
(adverse effects, methods)
- Young Adult
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