No increased risk of carcinogenesis with mesh-based hernia repairs.

Abstract

BACKGROUND:

The use of synthetic mesh has been placed under considerable scrutiny. We sought to evaluate whether there is a link between placement of synthetic polypropylene mesh for hernia repair and a subsequent cancer diagnosis.

METHODS:

Adult men undergoing mesh-based hernia repair from January 2008-December 2009 in New York State were identified and followed through December 2014. Control cohorts of men undergoing cholecystectomy and total knee replacement were control cohorts.

RESULTS:

1894 patients undergoing hernia repair, 912 patients in the cholecystectomy control cohort, and 1099 in the TKA control cohort with a cancer diagnosis. In the matched analyses of mesh-based hernia repair and cholecystectomy patients 6.5% vs. 7.1% developed cancer. In the matched analysis of hernia patients and TKA patients, 9.3% vs. 9.1% developed cancer. No association between mesh-based hernia surgery and increased risk of cancer was found.

CONCLUSIONS:

Mesh-based hernia repair was not associated with an increased risk of subsequent development of cancer in men.

• Authors: Bilal Chughtai, Art Sedrakyan, Dominique Thomas, Jialin Mao, Karyn S Eilber, J Quentin Clemens, Jennifer T Anger
• Journal: American journal of surgery (Am J Surg) Vol. 216 Issue 3 Pg. 481-486 (09 2018) ISSN: 1879-1883 [Electronic] United States
• PMID: 29233526 (Publication Type: Journal Article)
• Copyright: Copyright © 2017 Elsevier Inc. All rights reserved.

Chemical References

• Polypropylenes

Topics

• Carcinogenesis
• Follow-Up Studies
• Hernia, Ventral (surgery)
• Herniorrhaphy (methods)
• Humans
• Incidence
• Male
• Middle Aged
• Neoplasms (epidemiology, etiology)
• New York (epidemiology)
• Polypropylenes
• Postoperative Complications (epidemiology, etiology)
• Retrospective Studies
• Risk Assessment (methods)
• Surgical Mesh