The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
Also Known As:
Oncogenesis; Carcinogeneses; Oncogeneses; Tumorigeneses; Tumorigenesis
Networked: 88694 relevant articles (1643 outcomes, 11179 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Neoplasms (Cancer)
2. Inflammation (Inflammations)
3. Breast Neoplasms (Breast Cancer)
4. Neoplasm Metastasis (Metastasis)
5. Colitis


1. Zhang, Wei: 202 articles (08/2022 - 04/2002)
2. Wang, Wei: 168 articles (11/2022 - 01/2002)
3. Li, Wei: 161 articles (10/2022 - 01/2002)
4. Wang, Lei: 150 articles (08/2022 - 06/2003)
5. Li, Li: 139 articles (12/2022 - 05/2002)
6. Li, Yan: 139 articles (08/2022 - 10/2002)
7. Wang, Yan: 135 articles (11/2022 - 11/2002)
8. Tanaka, Takuji: 135 articles (01/2022 - 01/2001)
9. Wang, Jing: 124 articles (06/2022 - 10/2003)
10. Liu, Yang: 115 articles (09/2022 - 01/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Carcinogenesis:
1. Biomarkers (Surrogate Marker)IBA
2. AntioxidantsIBA
3. CarcinogensIBA
4. EnzymesIBA
5. Proteins (Proteins, Gene)FDA Link
6. anthraceneIBA
7. TeaIBA
8. DNA (Deoxyribonucleic Acid)IBA
9. AzoxymethaneIBA
10. CurcuminIBA

Therapies and Procedures

1. Therapeutics
12/01/2012 - " the best of our knowledge, this is the first report concerned two patients with CCM in a family, and the findings in this article suggest that CKS is a safe and effective adjuvant therapy for residual CCM after operation and NF2 gene mutation plays a role in tumorigenesis of pediatric intracranial CCM."
04/15/2021 - "In conclusion, a bioinformatic platform of gene-set integrative molecular functionomes and biophysiological pathways was constructed in this study to interpret the complicated pathogenic pathways of BOTs, and these important findings demonstrated the dysregulated immunological functionome and dysfunctional metabolic pathway as potential roles during the tumorigenesis of BOTs and may be helpful for the diagnosis and therapy of BOTs in the future."
01/01/2023 - "With the advancement of improved cellular manufacturing methods, novel cellular engineering strategies, precision genome editing technologies, and combination therapy approaches, we firmly believe that CAR-T cells will soon become an off-the-shelf, cost-effective, and potentially curative therapy for oncogenesis."
03/01/2010 - "Although PELP1 is important for normal functions of the ER, the possibility to target ER-PELP1 axis appears to be an effective strategy for preventing hormonal carcinogenesis and therapy resistance. "
12/01/2007 - "A comprehensive molecular understanding of the regulatory modules involved in carcinogenesis should also be important for improved identification of therapeutic targets and thus for future individualized therapy, e.g., by allowing therapeutic synergy when designing combination therapy against vulnerable points in the malignant cells. "
2. Chemoprevention
3. Drug Therapy (Chemotherapy)
4. Immunotherapy
5. Radiotherapy