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Knee Replacement Arthroplasty (Total Knee Replacement)

Subscribe to New Research on Knee Replacement Arthroplasty

Replacement of the knee joint.

Also Known As:

Total Knee Replacement; Arthroplasty, Replacement, Knee; Arthroplasties, Knee Replacement; Arthroplasties, Replacement, Knee; Arthroplasty, Knee Replacement; Knee Replacement Arthroplasties; Replacement Arthroplasties, Knee; Replacement Arthroplasty, Knee; Replacement, Total Knee; Knee Replacements, Total; Replacements, Total Knee; Total Knee Replacements; Knee Replacement, Total

Networked: 1330 relevant articles (61 outcomes, 177 trials/studies)

Relationship Network

Therapy Context: Research Results

Operative Surgical Procedures: 8
- Orthopedic Procedures: 290
  - Arthroplasty: 15327
    - Replacement Arthroplasty: 120
      - Knee Replacement Arthroplasty: 1330
- Prosthesis Implantation: 146
  - Replacement Arthroplasty: 120
    - Knee Replacement Arthroplasty: 1330

Experts

1.	Katz, Jeffrey N: 11 articles (01/2015 - 09/2004)
2.	Wylde, Vikki: 8 articles (06/2015 - 01/2011)
3.	Losina, Elena: 8 articles (01/2014 - 09/2004)
4.	Blom, Ashley W: 7 articles (06/2015 - 04/2009)
5.	Lo, Ngai-Nung: 7 articles (03/2013 - 08/2007)
6.	Brenkel, I J: 7 articles (10/2012 - 07/2005)
7.	Roos, Ewa M: 6 articles (10/2015 - 01/2003)
8.	Sengupta, Nishan: 6 articles (02/2012 - 09/2010)
9.	Gooberman-Hill, Rachael: 5 articles (06/2015 - 01/2011)
10.	Wylde, V: 5 articles (05/2015 - 12/2007)

Related Diseases

1.	Pain (Aches) 08/01/2011 - "The use of an unloader brace is effective in providing short-term pain relief and improved function; however, most patients subsequently opt for total knee replacement on the symptomatic knee." 01/01/2004 - "Primary care physicians and surgeons should be aware that primary and revision total knee replacement can be done safely and effectively for patients 90 years and older and result in years of marked pain relief for those patients." 10/01/2014 - "Successful management of chronic postsurgical pain following total knee replacement." 02/01/2009 - "In conclusion, this project to improve the appropriateness and comprehensiveness of nurse instructions to patients with the objective of managing pain following total knee replacement surgery effectively achieved significantly positive results." 12/01/2013 - "The main outcomes included the initial anterior pain relief, with higher scores using the Knee Society Score (that improved in 84% of the knees), and the eventual failure of the technique, including percentage of patients that required secondary total knee replacement (30% of the knees). "
2.	Arthritis (Polyarthritis) 10/01/1992 - "Despite our observations that knees with primary patellofemoral arthritis do not do as well after total knee replacement as those with tibio-femoral arthritis, this procedure remains the best treatment option. " 08/01/2006 - "With appropriate patient selection, bilateral total knee replacement performed under a single anaesthetic, or staged at a one-week interval, is a safe and effective method to treat bilateral arthritis of the knee." 09/01/2009 - "The authors performed a matched paired study between two groups: bi-unicompartmental (Bi-UKR) versus total knee replacements (TKR) for the treatment of isolated bicompartmental tibio-femoral knee arthritis with an asymptomatic patello-femoral joint. " 06/01/2007 - "Unicompartmental versus computer-assisted total knee replacement for medial compartment knee arthritis: a matched paired study." 09/01/2006 - "This study supports unicompartmental knee arthroplasty as a cost-effective alternative for the treatment of unicompartmental arthritis when the durability and function of a unicompartmental replacement are assumed to be similar to those of a primary total knee replacement. "
3.	Infection 09/01/2010 - "Although resection arthroplasty should be maintained as the gold standard in the surgical treatment of this problem, the first case shows a successful short-term outcome ofreimplantation of a patient with fungal infection of long-stemmed, revision total knee replacement. " 01/01/2005 - "Good outcomes, defined as a functional total knee replacement free from infection at least 6 months after reimplantation, were achieved in 79 % of the patients. " 01/01/2003 - "Two-stage reimplantation without using a cement spacer between stages for septic total knee replacement is tolerable for patients, simpler for surgeons and can achieve good results without recurrence of infection." 10/01/1990 - "There was a significantly greater risk of infection in revision total knee replacement (15.3%), ankle fusion (9.3%), subtalar fusion (5.8%), primary total knee replacement (5.7%), spinal fusion (5.7%) and revision total hip replacement (4.5%). " 05/01/2002 - "We believe that total knee replacement (TKR) is a safe and effective procedure for the management of haemophiliac joint arthropathy; however, the increased risk of infection and non-infective complications remain a cause for concern. "
4.	Osteoarthritis 03/01/2014 - "Total knee replacement (TKR) is a cost-effective treatment option for severe osteoarthritis (OA). " 08/01/2009 - "Total knee replacements provide cost effective treatment for debilitating conditions such as osteoarthritis. " 01/21/2015 - "A systematic review and meta-analysis of all studies published from January 2000 onward was performed to evaluate health-related quality of life after primary total knee replacement for osteoarthritis in patients with at least three years of follow-up. " 11/01/2014 - "The aim of this study was to compare the functional outcome of patients following unicompartmental knee replacement (UKR) using the Oxford domed lateral UKR to patients who underwent cruciate-retaining total knee replacement (TKR) for isolated osteoarthritis in the lateral compartment. " 06/01/2014 - "Cigarette smoking and risk of total knee replacement for severe osteoarthritis among Chinese in Singapore--the Singapore Chinese health study."
5.	Venous Thromboembolism 01/01/2011 - "This study compared uF1+2 levels in patients with symptomatic and non-symptomatic venous thromboembolism (VTE) after total knee replacement (TKR) and in event-free sex- and age-matched controls. " 07/03/2001 - "The present study was performed to determine an efficacious and safe dose of rNAPc2 for prevention of venous thromboembolism after elective, unilateral total knee replacement. " 09/01/2015 - "Trimodal venous thromboembolism prophylaxis in total knee replacement: A quality improvement project for best care practices." 09/01/2014 - "Patients undergoing total hip replacement (THR) or total knee replacement (TKR) surgery are at high risk of developing venous thromboembolism (VTE). " 08/20/2013 - "Pharmacologic thromboprophylaxis reduces the risk for venous thromboembolism after total hip replacement (THR) or total knee replacement (TKR). "

Related Drugs and Biologics

1.	Enoxaparin (Lovenox)
2.	rivaroxaban
3.	ximelagatran (Exanta)
4.	Thrombin
5.	Ondansetron (Zofran)
6.	Opioid Analgesics (Opioids)
7.	Warfarin (Coumadin)
8.	Tranexamic Acid (AMCA)
9.	apixaban
10.	melagatran

Related Therapies and Procedures

1.	Hip Replacement Arthroplasty (Total Hip Replacement)
2.	Osteotomy
3.	Analgesia
4.	Epidural Analgesia
5.	Replantation