Abstract | BACKGROUND:
Pertussis in young infants is a unique, severe, afebrile, cough illness that is frequently fatal. METHODS: All pertussis cases ≤120 days of age admitted to a pediatric intensive care unit in California between October 1, 2013, and April 25, 2015, were evaluated. RESULTS: Of 100 pertussis patients ≤120 days of age admitted to pediatric intensive care unit, there were 5 deaths. The white blood cell counts in the fatal cases were significantly higher than in the nonfatal cases. Thirty-four percent of patients were intubated, 18% received inotropic and/or vasoactive support, 22% received steroid, 4% received extracorporal membrane oxygenation, and 3% underwent exchange blood transfusion. The median age at the time of illness onset in the patients who died was 23 days. CONCLUSIONS:
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Authors | James D Cherry, Kristen Wendorf, Brooke Bregman, Deborah Lehman, Delma Nieves, John S Bradley, Wilbert H Mason, Linette Sande-Lopez, Merrick Lopez, Myke Federman, Tempe Chen, Dean Blumberg, Samantha Johnston, Hayden T Schwenk, Peggy Weintrub, Kevin K Quinn, Kathleen Winter, Kathleen Harriman |
Journal | The Pediatric infectious disease journal
(Pediatr Infect Dis J)
Vol. 37
Issue 3
Pg. 202-205
(03 2018)
ISSN: 1532-0987 [Electronic] United States |
PMID | 28737623
(Publication Type: Journal Article, Observational Study)
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Topics |
- Age Factors
- Bordetella pertussis
- Combined Modality Therapy
- Comorbidity
- Female
- Humans
- Infant
- Infant, Newborn
- Male
- Outcome Assessment, Health Care
- Public Health Surveillance
- Severity of Illness Index
- Whooping Cough
(diagnosis, epidemiology, mortality, therapy)
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