Abstract | BACKGROUND: METHODS: We analyzed 240 transplantation patients with preoperative renal dysfunction (estimated glomerular filtration rate <60 mL/min/1.73 m2). RESULTS: Compared with the non-dialytic conservative treatment group (n = 98), the intraoperative continuous renal replacement therapy group (n = 142) experienced more severe critical illness (as indicated by Model for End-Stage Liver Disease score) and more severe preoperative renal dysfunction, as well as more frequent hepatic encephalopathy, ventilatory care, and intensive care unit admission (P < .005). There were also worse outcomes regarding patient survival, graft survival, recovery of renal function, and postoperative complications. However, the intraoperative continuous renal replacement therapy group significantly escaped volume overload (adjusted odds ratio, 0.396; 95% confidence interval, 0.223-0.703; P = .002) and unnecessary changes in serum sodium concentration ≥10 mmol/L during surgery (adjusted odds ratio, 0.208; 95% confidence interval, 0.065-0.665; P = .008). CONCLUSIONS:
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Authors | S D Baek, M Jang, W Kim, H Yu, S Hwang, S-G Lee, G-S Hwang, E K Lee, S M Kim, J W Chang |
Journal | Transplantation proceedings
(Transplant Proc)
2017 Jul - Aug
Vol. 49
Issue 6
Pg. 1344-1350
ISSN: 1873-2623 [Electronic] United States |
PMID | 28736005
(Publication Type: Journal Article)
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Copyright | Copyright © 2017 Elsevier Inc. All rights reserved. |
Topics |
- Adult
- Aged
- Female
- Glomerular Filtration Rate
- Humans
- Intraoperative Care
(methods)
- Kidney
(physiopathology)
- Liver Diseases
(complications, physiopathology, surgery)
- Liver Transplantation
(methods)
- Male
- Middle Aged
- Odds Ratio
- Renal Insufficiency
(etiology, physiopathology, therapy)
- Renal Replacement Therapy
(methods)
- Retrospective Studies
- Treatment Outcome
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