Epilepsia partialis continua (
EPC) is a rare variant of
epilepsy. Cases from China are rare. We present a case series of seven patients to analyze its clinical features, imagining findings, etiology, drug use, and long-term outcome in a single
epilepsy center. We made assessments of drug effects twice (Stage I - when they left our hospital; Stage II in March 2017 - by telephone interviews to rate their long-term outcome). The mean duration of the second follow-up was 4.8years. Of the seven patients, four patients characterized motor and sensory
EPC and three motor
EPC. Local distributions of
EPC were: the left face (2 patients), right face (1 patient), left leg (3 patients), right leg and arm (1 patient). CT/MR was abnormal in four, normal in two, and not available in one patient. EEG abnormalities commonly consisted of spike-waves, sharp-waves (or) slow wave activity, and periodic lateralized epileptiform discharges. They were all nonprogressive
EPC (
encephalitis: 2;
tumor: 2;
head trauma: 1; and not found in 2 cases). In our observations,
topiramate might be effective in patients with facial muscles continuous jerking, while
carbamazepine in cases of limbs continuous
myotonia. Our cases had favorable long-term outcome. Thus, our cases' etiology differentiated from other regions. Some drugs used by referring to
EPC distributions might help to control
EPC and their outcome were usually favorable.