Hepatocellular carcinoma in a non-failing Fontan circulation.

Abstract

Patients after a Fontan operation exhibit some degree of fibrosis which are primarily located in a sinusoidal or centrilobular pattern. Cirrhosis may develop years later and the incidence of cancer is up to 5%. That is why some authors recommend that patients who are >10 years out from their Fontan operation should undergo cardiac assessment as well as the determination of alpha-fetoprotein level, the realization of liver imaging tests or even liver biopsy to stay ahead of neoplastic transformation.

• Authors: Efrén Martínez-Quintana, Alberto Monescillo, Fayna Rodríguez-González
• Journal: Revista espanola de enfermedades digestivas (Rev Esp Enferm Dig) Vol. 109 Issue 5 Pg. 375 (May 2017) ISSN: 1130-0108 [Print] Spain
• PMID: 28480728 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Carcinoma, Hepatocellular (diagnostic imaging, etiology)
• Fatal Outcome
• Female
• Fontan Procedure
• Humans
• Liver Neoplasms (diagnostic imaging, etiology)
• Magnetic Resonance Imaging
• Postoperative Complications (diagnostic imaging)