Directionally-sensitive peripheral nerve recording: bipolar nerve cuff design.

Abstract

Although bipolar nerve cuff electrodes (NCEs) are used in clinical neurostimulation therapies (e.g., epilepsy, obstructive sleep apnea), the use of this electrode as part of a closed-up controlled system is very limited. The literature points to high noise content (i.e., poor signal-to-noise ratio, SNR) as the primary reason for not using bipolar NCEs to record neural activity. In fact, over the past several decades, the pseudo-tripolar NCEs, the symmetric configuration of this electrode array (i.e., electrically-shorted side contacts) makes it very difficult to obtain directional information from the recorded neural activity (efferent vs. afferent). In this study, we investigated the feasibility of using a bipolar NCE to achieve low-noise, directionally-sensitive recording of peripheral nerve activity.

• Authors: Parisa Sabetian, Milos R Popovic, Paul B Yoo
• Journal: Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference (Annu Int Conf IEEE Eng Med Biol Soc) Vol. 2016 Pg. 6178-6181 (Aug 2016) ISSN: 2694-0604 [Electronic] United States
• PMID: 28269663 (Publication Type: Journal Article)

Topics

• Action Potentials
• Animals
• Electric Stimulation (methods)
• Electrodes
• Electrophysiology (instrumentation, methods)
• Humans
• Peripheral Nerves (physiology)
• Signal-To-Noise Ratio