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Obstructive Sleep Apnea

A disorder characterized by recurrent apneas during sleep despite persistent respiratory efforts. It is due to upper airway obstruction. The respiratory pauses may induce HYPERCAPNIA or HYPOXIA. Cardiac arrhythmias and elevation of systemic and pulmonary arterial pressures may occur. Frequent partial arousals occur throughout sleep, resulting in relative SLEEP DEPRIVATION and daytime tiredness. Associated conditions include OBESITY; ACROMEGALY; MYXEDEMA; micrognathia; MYOTONIC DYSTROPHY; adenotonsilar dystrophy; and NEUROMUSCULAR DISEASES. (From Adams et al., Principles of Neurology, 6th ed, p395)
Also Known As:
Sleep Apnea, Obstructive; Apnea, Obstructive Sleep; OSAHS; Obstructive Sleep Apnea Syndrome; Sleep Apnea Hypopnea Syndrome; Sleep Apnea Syndrome, Obstructive; Syndrome, Obstructive Sleep Apnea; Syndrome, Sleep Apnea, Obstructive; Syndrome, Upper Airway Resistance, Sleep Apnea; Apneas, Obstructive Sleep; Obstructive Sleep Apneas; Sleep Apneas, Obstructive; Upper Airway Resistance Sleep Apnea Syndrome
Networked: 9367 relevant articles (727 outcomes, 1487 trials/studies)

Relationship Network

Disease Context: Research Results

Related Diseases

1. Obstructive Sleep Apnea
2. Apnea
3. Hypertension (High Blood Pressure)
4. Snoring
5. Sleepiness

Experts

1. Gozal, David: 76 articles (01/2022 - 02/2002)
2. Malhotra, Atul: 59 articles (05/2022 - 03/2003)
3. Guilleminault, Christian: 48 articles (01/2021 - 01/2002)
4. Tufik, Sergio: 47 articles (10/2022 - 05/2006)
5. Cistulli, Peter A: 45 articles (01/2022 - 09/2002)
6. Redline, Susan: 43 articles (01/2022 - 06/2002)
7. Friedman, Michael: 39 articles (11/2022 - 12/2005)
8. White, David P: 39 articles (01/2022 - 03/2003)
9. de Vries, Nico: 38 articles (01/2022 - 11/2006)
10. Lorenzi-Filho, Geraldo: 37 articles (01/2022 - 01/2009)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Obstructive Sleep Apnea:
1. Oxygen (Dioxygen)IBA
2. SuspensionsIBA
3. Biomarkers (Surrogate Marker)IBA
4. Modafinil (Provigil)FDA Link
5. Acetaminophen (Paracetamol)FDA LinkGeneric
6. Atomoxetine Hydrochloride (Strattera)FDA LinkGeneric
7. Glucose (Dextrose)FDA LinkGeneric
8. oxybutynin (Tavor)FDA LinkGeneric
9. SteroidsIBA
10. salicylhydroxamic acid (SHAM)IBA

Therapies and Procedures

1. Continuous Positive Airway Pressure
2. Therapeutics
3. Occlusal Splints
4. Tonsillectomy
5. Bariatric Surgery