We report a case of recurrent
breast cancer with involvement of the right adrenal grand, which was resected using laparoscopic surgery. The patient was a 41-year-old woman who underwent duct-lobular
segmentectomy for
ductal carcinoma in situ. Histopathology showed microinvasion, and tested positive for ER and PR, but negative for HER2, so we applied radiation to the remaining breast and administered
tamoxifen. After 9 months, local recurrence was detected and quadrantectomy with axillary
lymph node dissection was performed. One year and 10 months later, local recurrence was again detected and a tumorectomy was performed. The adjuvant
therapy was changed to an
LH-RH analog plus
anastrozole and it was administered effectively for 5 years. Left ileal
metastasis appeared in the 2nd month after completion of the
adjuvant chemotherapy, so radiation was applied and an
LH-RH analog plus
exemestane administration was started. Three years passed without recurrence, but a right adrenal
tumor appeared on computed tomography. The
tumor grew over 6 months, so laparoscopic right
adrenalectomy was performed. Histopathologically, the
tumor tested positive for ER and PR, and negative for HER2 so we diagnosed
metastasis of
breast cancer, and administered an
LH-RH analog plus
exemestane. The patient's disease has not progressed in the 3 months since surgery.