Abstract | OBJECTIVE: This systematic review aimed to evaluate the scientific evidence on the efficacy of desensitizing mouthwashes for the treatment of dentin hypersensitivity (DH) and root sensitivity (RS). MATERIAL AND METHODS: A thorough search in MEDLINE, PubMed and Cochrane Plus Library was conducted up to February 2015. Randomized clinical trials, parallel, double-blinded and placebo-controlled, with a follow-up of at least 6 weeks, reporting changes on response to tactile stimuli, thermal/evaporative stimuli or patients' subjective assessment of the pain experienced during their daily life after the home use of desensitizing mouthwashes were considered for inclusion. RESULTS: The screening of titles and abstracts resulted in seven publications meeting the eligibility criteria. The desensitizing agents evaluated were potassium nitrate (n = 5), aluminium lactate (n = 1) and sodium fluoride (n = 1). A meta-analysis for each of the hypersensitivity stimuli was performed. Results demonstrated statistically significant reduction in sensitivity scores favouring test group when DH was assessed by means of patients' self-reported pain experience (SMD at 8 weeks = 0.77; 95% CI [0.23; 1.31]; P = 0.005). No significant effects were detected in response to tactile or thermal/evaporative stimuli. Meta-regression analysis demonstrated a tendency towards an increased effect favouring test group for the patients' subjective perception, whereas tactile and thermal/evaporative stimuli showed a slight tendency towards a reduction in the efficacy of the test mouthwash. CONCLUSIONS: There exists a tendency towards a decrease in DH or RS scores with time in both treatment groups, with significant differences in favour of test group when sensitivity is evaluated in terms of patients' self-reported sensitivity symptoms.
|
Authors | A Molina, M García-Gargallo, E Montero, A Tobías, M Sanz, C Martín |
Journal | International journal of dental hygiene
(Int J Dent Hyg)
Vol. 15
Issue 2
Pg. 84-94
(May 2017)
ISSN: 1601-5037 [Electronic] England |
PMID | 27762076
(Publication Type: Comparative Study, Journal Article, Meta-Analysis, Review, Systematic Review)
|
Copyright | © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd. |
Chemical References |
- Aluminum Compounds
- Dentin Desensitizing Agents
- Lactates
- Mouthwashes
- Nitrates
- Potassium Compounds
- Sodium Fluoride
- potassium nitrate
- aluminum lactate
|
Topics |
- Aluminum Compounds
(therapeutic use)
- Dentin Desensitizing Agents
(therapeutic use)
- Dentin Sensitivity
(prevention & control)
- Double-Blind Method
- Follow-Up Studies
- Lactates
(therapeutic use)
- Mouthwashes
- Nitrates
(therapeutic use)
- Pain Measurement
- Potassium Compounds
(therapeutic use)
- Randomized Controlled Trials as Topic
- Self Report
- Sodium Fluoride
(therapeutic use)
- Tooth Root
|