Abstract | INTRODUCTION: PRESENTATION OF CASES: Case 1 involved a 54-year-old man who had been diagnosed with MG based on symptoms and detection of anti- acetylcholine receptor antibody (ARAB). Computed tomography (CT) revealed an anterior mediastinal tumor 30mm in diameter. Prednisolone (PSL) and tacrolimus were administered without surgery at that time. Six years after diagnosis of MG, he was admitted to our hospital and underwent extended thymectomy. Pathological examination revealed type B2-B3 thymoma according to World Health Organization criteria, comprising 80% of the tumor with small cell carcinoma as 20%. Case 2 involved a 51-year-old woman. She had been diagnosed with MG based on eyelid ptosis and detection of ARAB. Ten years after diagnosis of MG, diaphragm elevation was detected on chest X-ray. CT revealed an anterior mediastinal tumor, 47mm in diameter. We suspected tumor invasion to the right phrenic nerve, right atrium, and superior vena cava. We therefore performed extended thymectomy after preoperative radiotherapy (40Gy). Pathological examination revealed squamous cell carcinoma. DISCUSSION: CONCLUSION:
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Authors | Nobuyasu Kurihara, Hajime Saito, Hiroshi Nanjo, Hayato Konno, Maiko Atari, Yoshitaro Saito, Satoshi Fujishima, Komei Kameyama, Yoshihiro Minamiya |
Journal | International journal of surgery case reports
(Int J Surg Case Rep)
Vol. 27
Pg. 110-112
( 2016)
ISSN: 2210-2612 [Print] Netherlands |
PMID | 27591911
(Publication Type: Journal Article)
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Copyright | Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved. |