Abstract | PURPOSE: Retrolaminar block (RLB) is a thoracic truncal block that can produce analgesia for the thoracic and abdominal wall. However, the characteristics of RLB are not well known. The aim of this study was to determine analgesic efficacy by measuring postoperative consume of patient-controlled analgesia (PCA), additional nonsteroidal antiinflammatory drug ( NSAID) rescue, and opioid rescue. Our secondary analysis included assessment of the chronological change in arterial levobupivacaine concentrations after the block. METHODS: RESULTS: The frequency of postoperative block PCA use was significantly high after RLB in 24 h [p = 0.01; 6 (3-12) vs. 2.5 (0.3-3) times, respectively]. There was no PCA use after 24 h in either group. There was no postoperative opioid rescue use throughout the study. After RLB and PVB, there was no significant difference in T max (p = 0.14; 15 ± 8 vs. 15 ± 8 min, respectively) and C max (p = 0.2; 0.9 ± 0.2 vs. 0.9 ± 0.3 µg/ml, respectively), and all the concentrations were below the threshold of local anesthetic systemic toxicity. CONCLUSION: Continuous RLB was not inferior to PVB except for the first 24 h, and was satisfactory after mastectomy. RLB showed safe, low peak arterial levobupivacaine concentrations.
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Authors | Takeshi Murouchi, Michiaki Yamakage |
Journal | Journal of anesthesia
(J Anesth)
Vol. 30
Issue 6
Pg. 1003-1007
(12 2016)
ISSN: 1438-8359 [Electronic] Japan |
PMID | 27518726
(Publication Type: Journal Article, Randomized Controlled Trial)
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Chemical References |
- Analgesics
- Analgesics, Opioid
- Anti-Inflammatory Agents, Non-Steroidal
- Levobupivacaine
- Bupivacaine
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Topics |
- Aged
- Analgesia, Patient-Controlled
(methods)
- Analgesics
(administration & dosage)
- Analgesics, Opioid
(therapeutic use)
- Anesthesia, General
- Anti-Inflammatory Agents, Non-Steroidal
(therapeutic use)
- Bupivacaine
(administration & dosage, analogs & derivatives)
- Double-Blind Method
- Female
- Humans
- Levobupivacaine
- Mastectomy, Modified Radical
(methods)
- Middle Aged
- Nerve Block
(methods)
- Pain, Postoperative
(drug therapy)
- Prospective Studies
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