Abstract | OBJECTIVE: METHOD: This nationwide study was conducted in the framework of the third survey of a surveillance program. Students, aged 10-18 years, were recruited from 27 provinces in Iran. The prevalence of cardiometabolic risk factors was compared in students with and without HW and MetS. The association of HW with different cardiometabolic risk factors was determined. RESULTS: The mean age of studied population was 14.73±2.41 years. Prevalence of HW and MetS was 3.3% and 4%, respectively. Sixty-nine (71.1%) participants with HW had MetS. The prevalence of obesity, elevated systolic blood pressure, hypercholesterolemia, and elevated alanine aminotransaminase (ALT) was significantly higher in subjects with HW phenotype and MetS than in their peers (p<0.05). A significant association was observed between HW and elevated levels of cholesterol and ALT, as well as between obesity and low HDL-C (p<0.05). CONCLUSIONS: The current findings serve as complementary evidence to previous studies, which have been mainly conducted among adults, suggesting that the HW phenotype is associated with cardiometabolic risk factors, especially with elevated cholesterol and ALT. The authors propose that, in primary care settings and in large epidemiological studies, the measurement of all MetS components can be replaced by studying HW as a screening tool for identifying children at high risk for cardiometabolic disorders.
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Authors | Roya Kelishadi, Fahimeh Jamshidi, Mostafa Qorbani, Mohammad Esmaeil Motlagh, Ramin Heshmat, Gelayol Ardalan, Silva Hovsepian |
Journal | Jornal de pediatria
(J Pediatr (Rio J))
2016 Sep-Oct
Vol. 92
Issue 5
Pg. 512-20
ISSN: 1678-4782 [Electronic] Brazil |
PMID | 27343636
(Publication Type: Journal Article)
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Copyright | Copyright © 2016. Published by Elsevier Editora Ltda. |
Chemical References |
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Topics |
- Adolescent
- Cardiovascular Diseases
(blood, complications)
- Child
- Cross-Sectional Studies
- Dyslipidemias
(blood, complications)
- Female
- Humans
- Hypertriglyceridemic Waist
(complications, epidemiology)
- Iran
(epidemiology)
- Male
- Metabolic Syndrome
(complications, epidemiology)
- Pediatric Obesity
(complications)
- Phenotype
- Prevalence
- Risk Factors
- Transaminases
(blood)
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