Abstract | OBJECTIVES: METHODS: RESULTS: Mean pleural adenosine deaminase levels differed significantly between Gram-negative and Gram-positive bacterial infections of the pleural space (191.8±32.1 U/L vs 81.0±16.9 U/L, p<0.01). The area under the receiver operator characteristic curve was 0.689 (95% confidence interval: 0.570, 0.792, p<0.01) at the cutoff value of 86 U/L. Additionally, pleural adenosine deaminase had a sensitivity of 63.2% (46.0-78.2%); a specificity of 73.7% (56.9-86.6%); positive and negative likelihood ratios of 2.18 and 0.50, respectively; and positive and negative predictive values of 70.6% and 66.7%, respectively. CONCLUSIONS:
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Authors | Ruolin Li, Junli Wang, Xinfeng Wang, Maoshui Wang |
Journal | Clinics (Sao Paulo, Brazil)
(Clinics (Sao Paulo))
Vol. 71
Issue 5
Pg. 271-5
(May 2016)
ISSN: 1980-5322 [Electronic] United States |
PMID | 27276396
(Publication Type: Journal Article, Observational Study)
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Chemical References |
- Biomarkers
- Adenosine Deaminase
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Topics |
- Adenosine Deaminase
(analysis)
- Adult
- Aged
- Biomarkers
(analysis)
- Clinical Enzyme Tests
- Diagnosis, Differential
- Female
- Gram-Negative Bacterial Infections
(diagnosis, microbiology)
- Gram-Positive Bacterial Infections
(diagnosis, microbiology)
- Humans
- Male
- Middle Aged
- Pleural Effusion
(enzymology, microbiology)
- Predictive Value of Tests
- Retrospective Studies
- Sensitivity and Specificity
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