HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Photopatterned Polydiacetylene Images Using a DNA Bio-Photomask.

Abstract
We describe a novel strategy to fabricate a well-defined polydiacetylene (PDA) supramolecular pattern on polyvinylidene fluoride (PVDF) membrane utilizing a DNA bio-photomask. By focusing on that, the absorption spectrum of DNA molecules having a λmax at 260 nm overlaps with the wavelength at which the photopolymerization of the diacetylene monomer occurs, DNA molecules are used to define specific patterns on PVDF membranes coated with diacetylene lipids by shielding the applied 254 nm UV light and consequently preventing the photopolymerization of the lipids. As a result, the DNA-covered regions retain the original white color on the membrane while the regions uncovered by DNA molecules undergo the color change to blue through the photopolymerization by 254 nm UV irradiation. On the basis of the selective illumination through a DNA photomask, we precisely manufacture specific patterns using a microarray spotting method and also demonstrate the capability of this strategy to achieve a novel colorimetric DNA sensor without any complicated process.
AuthorsYun Kyung Jung, Cheulhee Jung, Hyun Gyu Park
JournalACS applied materials & interfaces (ACS Appl Mater Interfaces) Vol. 8 Issue 24 Pg. 15684-90 (Jun 22 2016) ISSN: 1944-8252 [Electronic] United States
PMID27225667 (Publication Type: Journal Article)
Chemical References
  • Polyacetylene Polymer
  • Polymers
  • Polyvinyls
  • polyvinylidene fluoride
  • Polyynes
  • polydiacetylene
  • DNA
Topics
  • Colorimetry
  • DNA (chemistry)
  • Photochemistry
  • Polyacetylene Polymer
  • Polymers (chemistry)
  • Polyvinyls (chemistry)
  • Polyynes (chemistry)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: