Overview of PET Tracers for Brain Tumor Imaging.

Abstract

This article provides an overview of the key considerations for the development and application of molecular imaging agents for brain tumors and the major classes of PET tracers that have been used for imaging brain tumors in humans. The mechanisms of uptake, biological implications, primary applications, and limitations of PET tracers in neuro-oncology are reviewed. The available data indicate that several of these classes of tracers, including radiolabeled amino acids, have imaging properties superior to those of (18)F-fluorodeoxyglucose, and can complement contrast-enhanced magnetic resonance imaging in the evaluation of brain tumors.

• Authors: Akash Sharma, Jonathan McConathy
• Journal: PET clinics (PET Clin) Vol. 8 Issue 2 Pg. 129-46 (Apr 2013) ISSN: 1556-8598 [Print] United States
• PMID: 27157944 (Publication Type: Journal Article)
• Copyright: Copyright © 2013 Elsevier Inc. All rights reserved.