Multimodal Treatment of Skull Base Inflammatory Pseudotumor: Case Report.

Abstract

lnflammatory pseudotumor (IPT) is a rare, non-neoplastic inflammatory process. It is most commonly occurs in the orbit, but extension into brain parenchyma is uncommon. In a confirmed case of IPT, most cases show good improvement with steroid theraphy. A 50-year-old man with progressive left-eye visual disturbance and mass lesion was admitted in a hospital. A left orbital mass biopsy revealed what was highly suspected as an inflammatory pseudotumor. Steroid pulse therapy with dexamethasone, radiation therapy, and chemotherapy with amphotericin B were performed, but they were not effective in improving the condition of the patient. Revision open surgery was then performed. A follow-up brain enhancement computerized tomography showed an enlarged mass volume and hydrocephalus with periventricular enhancement. As an additional procedure, ventriculoperitoneal shunt and tuberculosis medication were administered. About 2 weeks later, clinical symptoms and radiologic findings improved. We present a case of intra-cranial IPT and discuss further treatment methods.

• Authors: Sang Gun Lee, Il Young Shin, Hyung Sik Hwang, Il Choi
• Journal: Brain tumor research and treatment (Brain Tumor Res Treat) Vol. 3 Issue 2 Pg. 122-6 (Oct 2015) ISSN: 2288-2405 [Print] Korea (South)
• PMID: 26605269 (Publication Type: Journal Article)