[Hodgkin disease revealed by a nephrotic syndrome: A case report].

Abstract

Pediatric nephrotic syndrome (NS) is most often idiopathic or primary but in rare cases, it can be secondary to neoplasia. We report on a case of steroid-resistant NS revealing as a paraneoplastic syndrome of Hodgkin disease (HD) in a 12-year-old boy. The onset of the NS can be earlier, later, or simultaneous to the HD. Treatment of the lymphoma allows the disappearance of the NS. In the case we observed, the diagnosis of HD was delayed because HD presented with an isolated, hilar adenopathy in the absence of retroperitoneal or peripheral locations. In children aged 10 years or more presenting with NS, steroid-resistant or otherwise, a possible paraneoplastic origin such as Hodgkin lymphoma should always be taken into consideration and eventually eliminated.

• Authors: M Cheptou, V Pichault, R Campagni, M-V Vodoff, M Fischbach, C Paillard
• Journal: Archives de pediatrie : organe officiel de la Societe francaise de pediatrie (Arch Pediatr) Vol. 22 Issue 12 Pg. 1268-71 (Dec 2015) ISSN: 1769-664X [Electronic] France
• Vernacular Title: Lymphome de Hodgkin révélé par un syndrome néphrotique : à propos d'un cas.
• PMID: 26598043 (Publication Type: Case Reports, English Abstract, Journal Article)
• Copyright: Copyright © 2015. Published by Elsevier SAS.

Topics

• Child
• Hodgkin Disease (complications, diagnosis)
• Humans
• Male
• Nephrotic Syndrome (etiology)