A rare combination of amniotic constriction band with osteogenesis imperfecta.

Abstract

Amniotic constriction bands and osteogenesis imperfecta are disorders arising from a collagen defect. We report a rare association of amniotic bands with osteogenesis imperfecta in a child. The child was born with multiple amniotic bands involving the right leg, both hands and both feet. Multiple fractures of long bones of lower limbs occurred in childhood due to trivial trauma. Deformities of the femur and tibia due to malunion with osteopenia and blue sclerae were present. The patient was treated with z plasty of constriction band of the right tibia and bisphosphonate for osteogenesis imperfecta. This rare association of both collagen diseases may provide further insight for the pathogenesis of these diseases.

• Authors: Krupa Hitesh Shah, Hitesh Shah
• Journal: BMJ case reports (BMJ Case Rep) Vol. 2015 (Nov 11 2015) ISSN: 1757-790X [Electronic] England
• PMID: 26561227 (Publication Type: Case Reports, Journal Article)
• Copyright: 2015 BMJ Publishing Group Ltd.

Chemical References

• Bone Density Conservation Agents
• Alendronate

Topics

• Alendronate (therapeutic use)
• Amniotic Band Syndrome (complications, diagnosis, diagnostic imaging, drug therapy)
• Bone Density Conservation Agents (therapeutic use)
• Bone Diseases, Metabolic (complications, pathology)
• Child, Preschool
• Femur (diagnostic imaging, pathology)
• Fractures, Bone (etiology, pathology)
• Humans
• Infant, Newborn
• Male
• Osteogenesis Imperfecta (complications, diagnosis, diagnostic imaging, drug therapy)
• Radiography
• Tibia (diagnostic imaging, pathology)