Paradoxical worsening of tuberculous chorioretinitis in a Chinese gentleman.

Abstract

We report a case of paradoxical worsening of tuberculous chorioretinitis after initiation of anti-tuberculous therapy (ATT). The patient had left panuveitis with tuberculous chorioretinitis and was started on systemic ATT and oral steroids a week later. However, he developed paradoxical worsening 2 months after initiation of therapy. He was continued on ATT, oral steroids and intravitreal amikacin with resolution of the chorioretinal lesion subsequently. Ocular tuberculosis often poses a diagnostic challenge, and clinicians should be aware of the possibility of paradoxical worsening despite appropriate ATT. Clinicians should strongly consider starting oral steroids concurrently with ATT when managing ocular tuberculosis.

• Authors: Rosalynn Grace Siantar, Su Ling Ho, Rupesh Agrawal
• Journal: Journal of ophthalmic inflammation and infection (J Ophthalmic Inflamm Infect) Vol. 5 Pg. 21 ( 2015) ISSN: 1869-5760 [Print] Germany
• PMID: 26180557 (Publication Type: Journal Article)