EXPERIMENTAL-MORPHOLOGICAL SUBSTANTIATION OF EXPEDIENCY TO USE THE SKIN GLUE "DERMABOND" FOR POSTOPERATIVE WOUND CLOSURE.

Abstract

We aimed to investigate the morphological features of healing of postoperative wounds in the early stages of reparative process in the experiment, depending on the used type of the wound closure. It is proved that the nature and type of the scar depends on the processes that occur in the wound at the early postoperative stage, which in turn greatly affects the form of suture material used. The experiment included 20 male rats, weighing 180-200 g. All rats were anesthetized by a single intraperitoneal injection of sodium thiopental. After the shaving operative field, 2 cm full-thickness incision wound was made on the anterior surface of the abdomen in the longitudinal direction. As suture material for wound closure in the 1st experimental group (10 rats) we used surgical filament "Polyamide 4-0». In the 2nd experimental group (10 rats) wounds were closured by using skin glue "Dermabond". According from our experiment, the usage of skin glue creates better conditions for wound healing. Thus, to achieve a more aesthetic scar, we recommend applying skin glue instead of using nodal joints.

• Authors: D Avetikov, K Loza, I Starchenko, E Loza, M Marushchak
• Journal: Georgian medical news (Georgian Med News) 2015 Jul-Aug Issue 244-245 Pg. 90-3 ISSN: 1512-0112 [Print] Georgia (Republic)
• PMID: 26177141 (Publication Type: Journal Article)

Chemical References

• Cyanoacrylates
• octyl 2-cyanoacrylate

Topics

• Abdomen (pathology, surgery)
• Animals
• Cyanoacrylates (therapeutic use)
• Dermatologic Surgical Procedures
• Humans
• Male
• Postoperative Period
• Rats
• Suture Techniques
• Wound Closure Techniques
• Wound Healing