[Generalized morphea-like progressive systemic sclerosis with anticentromere antibodies and eosinophilic cellulitis].

Abstract

A 67-year-old woman without any history of exposure to organic solvents suffered from Raynaud's phenomenon, sclerodactylia, contracture of finger joints, diffuse pigmentation, pulmonary fibrosis, and generalized morphea-like eruptions on the trunk; she was diagnosed as generalized morphea-like progressive systemic sclerosis. She had a high titer of anticentromere antibody in her serum without any symptoms of CREST syndrome. She also had eosinophilic cellulitis on her extremities, which subsided within 6 months, and seemed to be due to a hypersensitivity reaction to mosquito bites. The occurrence of these two diseases together in our case may suggest some similarities in their pathogenesis.

• Authors: T Sasaki, H Nakajima, Y Kameda
• Journal: Nihon Hifuka Gakkai zasshi. The Japanese journal of dermatology (Nihon Hifuka Gakkai Zasshi) Vol. 99 Issue 4 Pg. 469-76 (Apr 1989) ISSN: 0021-499X [Print] Japan
• PMID: 2614990 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Autoantibodies

Topics

• Aged
• Autoantibodies (analysis)
• Cellulitis (complications)
• Centromere (immunology)
• Chromosomes (immunology)
• Eosinophilia (complications)
• Female
• Humans
• Scleroderma, Localized (pathology)
• Scleroderma, Systemic (complications, immunology)
• Skin (pathology)