Abstract | AIMS: MAIN METHODS: Spontaneous ventilation and paw withdrawal responses to nociceptive thermal stimulation were measured in anesthetized rats simultaneously. The efferent discharge of the phrenic nerve was recorded in anesthetized, vagotomized, paralyzed and artificially ventilated rats. KEY FINDINGS: SIGNIFICANCE:
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Authors | Satoko Kimura, Yoshiaki Ohi, Akira Haji |
Journal | Life sciences
(Life Sci)
Vol. 127
Pg. 32-8
(Apr 15 2015)
ISSN: 1879-0631 [Electronic] Netherlands |
PMID | 25744400
(Publication Type: Journal Article)
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Copyright | Copyright © 2015 Elsevier Inc. All rights reserved. |
Chemical References |
- Analgesics, Opioid
- Phosphodiesterase 4 Inhibitors
- Phosphodiesterase Inhibitors
- Caffeine
- Morphine
- Rolipram
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Topics |
- Analgesics, Opioid
(pharmacology, toxicity)
- Animals
- Caffeine
(pharmacology)
- Male
- Morphine
(pharmacology, toxicity)
- Pain Measurement
(drug effects)
- Phosphodiesterase 4 Inhibitors
(pharmacology)
- Phosphodiesterase Inhibitors
(pharmacology)
- Phrenic Nerve
(drug effects)
- Rats
- Rats, Wistar
- Respiration Disorders
(chemically induced, prevention & control)
- Respiratory Mechanics
(drug effects)
- Rolipram
(pharmacology)
- Vagotomy
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