A comparison of 120 W laser photoselective vaporization versus transurethral resection of the prostate for bladder outlet obstruction by prostate cancer.

Abstract

OBJECTIVE:

To compare the mid-term outcomes of photoselective vaporization of prostate (PVP) with GreenLight HPS 120 W laser and transurethral resection of the prostate (TURP) for obstructive lower urinary tract symptoms (LUTS) in men with prostate cancer (CaP).

PATIENTS AND METHODS:

Seventy four patients with locally advanced (T3/T4) CaP with severe LUTS or acute urinary retention (AUR) were allocated to TURP (n = 36) or PVP (n = 38). International Prostate Symptom Scores (IPSS), maximum flow rates (Qmax) and post-void residual volumes (Vres), PSA levels, prostate volumes, complications, catheter removal and hospitalization periods were recorded. Patients were reassessed at 3, 6, and 12 months.

RESULTS:

The catheter removal time was significantly longer in the TURP group (3.8 ± 1.1 vs. 1.2 ± 0.7 days, p = 0.02), whereas failure of initial voiding trial was higher in PVP (2.7 vs. 13.1%, p = 0.01). No significant difference in IPSS, Qmax and Vres values was observed within the follow-up period between two groups. A significant difference in urethral stricture rate (8.3 vs. 0%), catheter removal time (3.8 ± 11 vs. 1.2 ± 0.7 days) and hospital stay (2.9 ± 0.6 vs. 1.1 ± 0.5 days) was observed in favor of PVP.

CONCLUSIONS:

Palliative PVP is very safe and effective by means of symptomatic relief in patients with locally advanced CaP.

• Authors: Bulent Altay, Bulent Erkurt, Murat Can Kiremit, Rahim Horuz, Vahit Guzelburc, Selami Albayrak
• Journal: Urologia internationalis (Urol Int) Vol. 94 Issue 3 Pg. 326-9 ( 2015) ISSN: 1423-0399 [Electronic] Switzerland
• PMID: 25721931 (Publication Type: Comparative Study, Journal Article)
• Copyright: 2015 S. Karger AG, Basel

Chemical References

• Prostate-Specific Antigen

Topics

• Aged
• Aged, 80 and over
• Catheterization
• Hospitalization
• Humans
• Laser Therapy (methods)
• Lasers
• Lower Urinary Tract Symptoms (etiology, surgery)
• Male
• Middle Aged
• Postoperative Complications
• Prostate (surgery)
• Prostate-Specific Antigen (blood)
• Prostatic Neoplasms (complications, surgery, therapy)
• Transurethral Resection of Prostate (adverse effects)
• Treatment Outcome
• Urinary Bladder Neck Obstruction (etiology)