Glomerular disease in 2014: advances in basic science and translational medicine.

Abstract

Knowledge of the pathogenesis of glomerular disease and approaches to therapy continued to advance in 2014. Key studies identified thrombospondin type-1 domain-containing protein 7A as an antigenic target in primary membranous nephropathy, and demonstrated efficacy of rituximab as maintenance therapy in relapsing or steroid-dependent nephrotic syndrome and antineutrophil cytoplasmic antibody-associated vasculitis.

• Authors: Fernando C Fervenza, Sanjeev Sethi
• Journal: Nature reviews. Nephrology (Nat Rev Nephrol) Vol. 11 Issue 2 Pg. 67-8 (Feb 2015) ISSN: 1759-507X [Electronic] England
• PMID: 25584803 (Publication Type: Journal Article)

Topics

• Humans
• Kidney Diseases (drug therapy)
• Kidney Glomerulus
• Translational Research, Biomedical