Relationship between premature ejaculation and chronic prostatitis/chronic pelvic pain syndrome.

Abstract

INTRODUCTION:

Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common etiology of premature ejaculation (PE). However, the current data are insufficient to explain this relationship and to support routine screening of men with PE.

AIMS:

This study aims to evaluate the relationship between PE and CP/CPPS.

METHODS:

A cross-sectional study was conducted that included 8,261 men who had participated in a health examination. The Premature Ejaculation Diagnostic Tool (PEDT), the National Institutes of Health-Chronic Prostatitis Symptom Index (NIH-CPSI), and the International Index of Erectile Function-5 (IIEF) were used for assessment of symptoms. A full metabolic work-up and serum testosterone level checks were also performed. We then investigated the relationship using the Spearman correlation test, multiple linear regression, and logistic regression analyses.

MAIN OUTCOME MEASURES:

Associations of PEDT with NIH-CPSI.

RESULTS:

The mean age was 50.4 ± 5.5 years. In total, 2,205 (24.9%) men had prostatitis-like symptoms (NIH-CPSI pain score of ≥4 and perineal or ejaculatory pain), and 618 (7.0%) men had moderate to severe symptoms (NIH-CPSI pain score of ≥8). Additionally, 2,144 men (24.2%) were classified as demonstrating PE (PEDT > 10). The PEDT score was found to have a significant positive correlation with the NIH-CPSI pain domain score (correlation coefficient = 0.206; P < 0.001). After adjusting for age, metabolic syndrome status, testosterone level, and IIEF score, there was no change in the positive correlation between the NIH-CPSI pain domain score and PEDT score (Beta = 0.175; P < 0.001). After adjusting for age, testosterone level, metabolic syndrome, and IIEF score, the odds ratio (OR) for PE significantly increased with the severity of pelvic pain (mild prostatitis-like symptoms, OR for PE: 1.269, 95% confidence interval: 1.113-1.447; moderate to severe symptoms, OR for PE: 2.134: 95% confidence interval: 1.782-2.557).

CONCLUSIONS:

Our data showed a significant correlation between the PEDT score and the NIH-CPSI score. We suggest routine screening for CP/CPPS in men with PE and PE in men with CP/CPPS.

• Authors: Jun Ho Lee, Sung Won Lee
• Journal: The journal of sexual medicine (J Sex Med) Vol. 12 Issue 3 Pg. 697-704 (Mar 2015) ISSN: 1743-6109 [Electronic] Netherlands
• PMID: 25475760 (Publication Type: Journal Article)
• Copyright: © 2014 International Society for Sexual Medicine.

Topics

• Adult
• Chronic Disease
• Coitus (psychology)
• Cross-Sectional Studies
• Humans
• Male
• Mass Screening
• Middle Aged
• Odds Ratio
• Pelvic Pain (complications, physiopathology, psychology)
• Premature Ejaculation (etiology, physiopathology, psychology)
• Prostatitis (complications, physiopathology, psychology)
• Surveys and Questionnaires
• United States