Biomarkers in pediatric heart disease.

Abstract

A biomarker is a characteristic that can be used as an indicator of a biological state. A biomarker can be a clinical observation, laboratory test or an imaging parameter. In this review, we discuss the use of biomarkers in differentiating cardiac from noncardiac disease; predicting the prognosis of patients with heart failure, pulmonary hypertension and dilated cardiomyopathy; diagnosing subclinical cardiac involvement in muscular dystrophy and postchemotherapy cancer patients; detecting acute rejection following heart transplantation; diagnosing Kawasaki disease; aiding the management of postoperative cardiac patients; and managing both common (tetralogy of Fallot) and complex (single-ventricle physiology) congenital heart diseases.

• Authors: Hythem Nawaytou, Harold S Bernstein
• Journal: Biomarkers in medicine (Biomark Med) Vol. 8 Issue 7 Pg. 943-63 ( 2014) ISSN: 1752-0371 [Electronic] England
• PMID: 25307548 (Publication Type: Journal Article, Review)

Chemical References

• Biomarkers

Topics

• Adolescent
• Biomarkers (blood)
• Child
• Child, Preschool
• Heart Diseases (blood, diagnosis)
• Humans
• Pediatrics