[Granulomatous dermatitis caused by surfen in diabetics treated with Insulin-depot-S-Richter].

Abstract

Two cases of local cutaneous reaction in diabetics treated with Insulin-depot-S-Richter are reported. Intracutaneous test and histological examination revealed that the granulomatous inflammation of the skin was due to surfen. Insulin-depot-S-Richter was changed to insulin preparation free from surfen (Monotard MC, Novo) and no further local reactions could be observed in the same patients.

• Authors: G Jermendy, E Szabó
• Journal: Orvosi hetilap (Orv Hetil) Vol. 130 Issue 34 Pg. 1825-8 (Aug 20 1989) ISSN: 0030-6002 [Print] Hungary
• Vernacular Title: Surfen okozta granulomás börgyulladás Insulin-depot-S-Richter terápia kapcsán.
• PMID: 2528707 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Delayed-Action Preparations
• Hypoglycemic Agents
• Insulin
• aminoquinuride
• Urea

Topics

• Delayed-Action Preparations
• Diabetes Mellitus, Type 1 (drug therapy)
• Drug Eruptions (etiology, pathology)
• Female
• Granuloma (chemically induced, pathology)
• Humans
• Hypoglycemic Agents (adverse effects)
• Insulin (administration & dosage, adverse effects)
• Male
• Middle Aged
• Skin (pathology)
• Urea (administration & dosage, adverse effects, analogs & derivatives)